The Neurobiology of Ecstasy

People also describe serious body pain during the crash. Their whole body aches and seems to hurt. The pain is often most intense in people s jaws. Between the depression and physical aches of Ecstasy use, many people make the mistake of feeling that the only way to escape is to take more Ecstasy. Sadly, users often find themselves trying again and again, for years after, to achieve the same feeling that they got the first time they used Ecstasy. They do not realize that it is biologically impossible for them to succeed. 

Feeling this way, she had no way of knowing the sadness and depression that would soon follow. 

Serotonin leuptake channel (reduces synaptic serotonin leveis) 

This causes the postsynaptic neuron to be overstimulated by serotonin. 

It had been weeks since Hannah s first rave. . . weeks since her first experience with X. She wasn t really hanging out with Amanda anymore, either. Hannah had seen her around at a few places since then, but they just hung in different circles now. 

---

National Institute on Drug Abuse. The Neurobiology of Ecstasy. Accessed at http //www.drugabuse.gov/pubs/teaching/Teaching4/Teaching.html. 

---