The Mechanism of Molybdenum Nitrogenase

A comprehensive description of the mechanism of molybdenum nitrogenase has been provided by the Lowe-Thorneley scheme 102) (Figs. 8 and 9). In this scheme the Fe protein (with MgATP) functions as a single electron donor to the MoFe protein in the Fe protein cycle (Fig. 8), which is broken down into four discrete steps, each of which may be a composite of several reactions  

The reduced Fe protein MgATP complex forms a complex with the MoFe protein 

An electron is transferred from the Fe protein to the MoFe protein with concomitant hydrolysis of MgATP to MgADP and Pi 

The oxidized Fe protein MgADP complex dissociates from the reduced MoFe protein 

The Fe protein is reduced by Na2S204 and the MgADP is replaced by MgATP 

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