The formation of poly heteroaryl compounds

In 2012, Tu et alP demonstrated that robust acenaphthoimidazolydiene PEPPSl-based Pd-complex 78 (0.5 mol%) could be used to effectively couple (hetero)arylboronic 

More recently, Ktigtikbay and co-workers investigated the microwave-assisted Suzuki-Miyaura coupling of 2- and 3-halopyridines using a PdfOAcl /benzimidazo-lium salt catalyst system and K COj as the base. All complexes were reported to have similar activity with the exception of complex 93, which was found to be the least active in Suzuki-Miyaura coupling. In general, heteroaryl chlorides were found to be less reactive than the bromide analogs. In addition, 3-halopyridines were found to couple more efficiently than 2-halopyridines (Table 4). 

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