The Fate of Acetyl-CoA from Fatty Acids Ketogenesis

6 THE FATE OF ACETYL-CoA FROM FATTY ACIDS KETOGENESIS 

Acetyl-CoA is oxidized to carbon dioxide via the citric acid cycle (Chap. 12), thus transforming additional energy to that which has been transformed via /3-oxidation. In liver mitochondria only, acetyl-CoA may also be converted to ketone bodies  

The reactions and the biosynthetic pathway for these compounds are shown in Table 13.2 and Fig. 13-6. 

Normally, some acetoacetate is converted to 3-hydroxybutyrate. Acetoacetate and 3- 

3-Hydroxybutyrate and acetone are derived from acetoacetate CHjCOCHjCOO  

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