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The Coupling-Addition Sequence

1 Sonogashira Coupling of Highly Electron-Deficient Heterocycles to Activated Alkynes and Subsequent Amine Addition [Pg.31]

2 Modified Sonogashira Coupling of Acid Chlorides to Alkynones [Pg.32]

A carbonyl group in conjugation with the triple bond exerts a strong polarization of the alkyne. Thus, Sonogashira coupling of acid chlorides 7 and terminal alkynes [Pg.32]


See other pages where The Coupling-Addition Sequence is mentioned: [Pg.211]    [Pg.31]    [Pg.34]   


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