The biosynthesis of IPP and DMAPP

A second pathway for the biosynthesis of IPP and DMAPP eluded discovery until the 1990s but was then rapidly elucidated in considerable detail (deoxyxylulose pathway, Figure 8). These events have been reviewed repeatedly and will not be discussed at this point suffice it to say that retrobiosynthetic analysis has been involved to some extent in the elucidation of the nonmevalonate pathway (specific examples are given in Eisenreich et al.51). 

Figure 3.6 The biosynthesis of IPP and DMAPP from 1 -deoxyxylulose 5-phosphate.

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