THE ADAPTED HEART

In 1986 Murry, Jennings and Reimer made the observation that brief episodes of ischemia and reperfiision have the ability to adapt the heart to a subsequent prolonged episode of ischemia followed by reperfusion and this phenomenon is known as ischemic preconditioning.192 This form of adaptation consists of an early transient phase lasting hours (classic or early preconditioning) and a late phase, lasting 1 to 3 days (delayed 

Phosphorylated p54 and p46 JNKs expression Heat Normal Heal Normal 

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