Teucrium oliverianum

From Teucrium oliverianum [34,68] the two C-10 hydroxylated neo-clerodane diterpenes were isolated, teucrolivins B (115) and A (116). Both possess a C-103 hydroxyl group appeared at 8 81.53 and 81.73, respectively, the 3-configuration of them was supported by NOE experiments, which showed that C-20 methyl group and the H-1 a proton must be close (3.7 % NOE enhancement in H-1 a when the Me-20 protons were irradiated). The NOE experiments summarized in Table 15 clearly revealed that the relative stereochemistry of the substituents of decalin ring of teucrolivin B is that depicted in its formula 115. 

---