Tetraoxanes, synthesis

A practical synthesis has been claimed for the cycHc tetramer of formaldehyde, 1,3,5,7-tetraoxane [293-30-17, which has a boiling point of 175°C and a melting point of 112°C (155). It has found some use in textde treatment in Japan. 

As noted in the previous section, Vennerstrom and coworkers have carried out a large amount of research into the synthesis of tetraoxanes, e.g. 72, 73a and 73b, some of which have proven to be highly potent in For the synthesis of symmetrical... 

General methods for the preparation of 1,2,4,5-tetraoxanes Key structures for the development of peroxidic antimalarial agents 12KGS60. Reactions oftetrazines with dienophiles 12KGS1237. 1,2,4,5-Tetrazines and azolo[l,2,4,5]tetrazines Synthesis and reactions with nucleophiles 13KGS75. 

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