Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Tetrahedral intermediate of esters

Figure 10.18 Catalytic monoclonal antibody (MAb) mediated ester hydrolysis. The MAb was generated through immunoreaction with the illustrated hapten linked to an appropriate carrier protein. The part of the hapten related to the substrate structure is shown in red. The phosphonate link is used as a transition state analogue of the rate determining step transition state leading to the key tetrahedral intermediate of ester hydrolysis. The MAb should optimally bind the rate determining step transition state relative to substrate or products in order to effect maximum catalytic effect. Figure 10.18 Catalytic monoclonal antibody (MAb) mediated ester hydrolysis. The MAb was generated through immunoreaction with the illustrated hapten linked to an appropriate carrier protein. The part of the hapten related to the substrate structure is shown in red. The phosphonate link is used as a transition state analogue of the rate determining step transition state leading to the key tetrahedral intermediate of ester hydrolysis. The MAb should optimally bind the rate determining step transition state relative to substrate or products in order to effect maximum catalytic effect.
See also in sourсe #XX -- [ Pg.850 , Pg.851 , Pg.856 , Pg.876 ]

See also in sourсe #XX -- [ Pg.850 , Pg.851 , Pg.856 , Pg.876 ]

See also in sourсe #XX -- [ Pg.850 , Pg.851 , Pg.856 , Pg.876 ]

See also in sourсe #XX -- [ Pg.792 , Pg.793 , Pg.798 , Pg.820 ]



SEARCH



Intermediate esters

Tetrahedral intermediate

Tetrahedral intermediate in reaction of esters with ammonia

© 2024 chempedia.info