Tetracyclines tetracycline-specific antibodies

Cennamo et al. [103] developed a SPR based sensor with a MIP layer of about 150 nm. This sensor was able to specifically recognize L-nicotine and not D-nicotine at a low concentration relevant for samples in the field. Other examples of MIP based SPR sensors are the sensor by Verma and Gupta [104] detecting the antibiotics tetracycline and their vitamin B3 sensor [105] for which the MIPs were prepared in hydrogel. Lotierzo et al. [106] developed an SPR based sensor for domoic acid, a neurotoxin. They compared their sensor with a sensor based on monoclonal antibodies and found that the MIP based sensor could be regenerated without losing its functionality and had a three times lower detection limit compared to the immunosensor. 

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