2-tert-Butylsulfonylpyrazine

Apart from the pyrolysis of 2-tert-butylsulfonylpyrazine to afford pyrazine (1) [in 49% yield with loss of sulfur dioxide and unsaturated ( ) hydrocarbon]239 and the reduction of pyrazine to piperazine (2) (in 76% yield by treatment of an alkaline solution with Ni—A1 alloy),479 no new or improved routes to pyrazine or piperazine appear to have been reported in recent years nor has any di- or tetrahy-dropyrazine been prepared. Both pyrazine and piperazine are now available commercially at modest cost. 

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