Temporary silicon-tethered RCM

Temporary Silicon-tethered RCM (TST-RCM) of Enyne and Dienyne Temporary silicon-tethered strategies of enyne and dienyne metathesis have been studied to demonstrate the stereoselective formation of acyclic tri- and tet-rasubstituted 1,3-dienes to circumvent the problems with controlling chemo-, regio-, and stereoselectivity in the CM... 

Z.2 Temporary Silicon-Tethered Ring-Closing Metathesis Reactions 245 Table 8.5 TST-RCM reactions of acyclic mono-alkoxysilanes. 

Several approaches to what are formally Si-0 and O-Si-O heterocycles have been reported, although these reactions invariably involve the use of the Si-O bond only as a temporary tether. The coupling and RCM of dissymmetric alcohols was reported by Eustache and co-workers <01TL239> and this method was applied in the synthesis of attenol A <020L4105>. Denmark and Yang performed the RCM of Si-O tethered dienes in tandem with silicon-assisted cross-... 

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