Tebbe reagent synthesis

Scheme 20. Synthesis of hexacyclic polyether 138. (a) 4.0 equiv of Tebbe reagent (93), THF, 25 °C, 0.5 h then reflux, 10 h, 71% (b) BH3 then H202 (c) Dess-Martin reagent, 60% for two steps (d) TBAF, 60% (e) Et3SiH, BF3.Et20,91% (Nicolaou et al.) [34a]...

See The Petasis modification of the Tebbe Reagent.1 N. A. Petasis, Encyclopedia of Reagents for Organic Synthesis, John Wiley and Sons, Inc., L. A. Paquette, Ed., New York, 1995 1, 470 [1271-66-5]... 

Sinay and co-workers described the synthesis of isopropenyl glycosides [169] by reaction of the corresponding anomeric acetates with the Tebbe reagent [170]. Reaction of 1-0-acetyl-... 

Recently, Claisen rearrangement of allyl-vinyl ether prepared from glycal ester with Tebbe reagent was reported [91]. In contrast to the Ireland-Claisen rearrangement, in principle, a non-enolizable ester can be employed (O Scheme 63). This method was applied for the synthesis of C-disaccharide. 

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