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Taxoid Libraries from Baccatin III

This is the first of two syntheses included in this chapter to highlight how natural product-based scaffolds can be attached to a resin for convenient derivatization into libraries. The other example is the synthesis of sarcodic-tyin libraries described in the next section. In both cases, interesting libraries were made with minimal development time by performing scaffold construction in solution or obtaining it from a natural source. [Pg.256]

RECENT ADVANCES IN SOLID-PHASE SYNTHESIS OF NATURAL PRODUCTS [Pg.258]

Scheme 6 describes the taxoid library synthesis.28 The supported and highly functionalized intermediate 48 was produced from baccatin III 47 in several steps. These involved elaboration of baccatin III in solution by... [Pg.256]

See other pages where Taxoid Libraries from Baccatin III is mentioned: [Pg.256]    [Pg.257]    [Pg.256]    [Pg.257]    [Pg.256]    [Pg.257]    [Pg.256]    [Pg.257]    [Pg.222]    [Pg.155]    [Pg.155]   


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