Tau-fluvalinate

Tau-fluvalinate (II) Tefluthrin (I) Not likely to be a human carcinogen [102]. In female rats, there was evidence of carcinogenicity in the form of uterine adenocarcinomas. Benign liver tumors were observed in female mice. Tefluthrin did not cause cancer in male mice or rats. There was no evidence that tefluthrin was genotoxic. Cancer risks are not of concern in humans [103], No evidence of carcinogenicity was demonstrated in studies conducted with mice or rats [104],... 

Yang G-S, Vazquez PP, Frenich AG, Vidal M, Aboul-Enein HY (2004) Separation and simultaneous determination of enantiomers of tau-fluvalinate and permethrin in drinking water. Chromatographia 60 523-526... 

A large number of synthetic pyrethroids with a variety of aromatic and aliphatic fluorine substituents have been commercialized, and will be discussed in the sections on fluorinated ether, aromatic fluorine, and fluorinated aliphatic groups, respectively. Fluvalinate (Mavrik ) [50] is a trifluoromethylphenyl pyrethroid, initially introduced by Zoecon (later Zandos Ag) and later replaced by tau-fluvalin-ate, which contains two of the four isomers of fluvalinate. Tau-fluvalinate (Apistan ) is a synthetic pyrethroid used for the topical treatment of honeybees against the parasitic mite Varroa jacobsoni. Mite resistance to tau-fluvalinate has been reported [51],... 

Torero Control of mites Vegetables, vines, others Twinpack with 500 mL clofentezine 20 SC + 300 mL tau-fluvalinate 24 SC... 

In the last century, the development of organophosphorus, carbamate, and organochloride insecticides was followed by synthetic pyrethroids. As a result, pyrethroids are now used frequently in the domestic milieu. Pyrethroid insecticides are synthetically derived from the molecular structure or sharing the same mechanism of action of natural pyrethrins that have broader spectmm of activity, more stability, and residual activity (persists longer than that of natural pyrethrins) and include the following allethrin, cyfluthrin, cyhalothrin, cypermethrin, deltamethrin, fenvalerate, flumethrin, fluvalinate, tau-fluvalinate, and permethrin (see structure in Fig. 137.2). They are lipophilic compounds and generally of low acute oral toxicity to mammals but are very toxic to aquatic organisms. When synthetic pyrethroids are administered to mammals parenterally, the synthetic pyrethroids are neurotoxic. 

Tau-fluvalinate (contains two of four isomers of racemic mixture, fluvalinate) Topically treatment Honeybees Parasitic mite Varroa jacobsoni Polymer matrix strip (8 g in weight crmtaining 800 mg tau-iluvalinate suspended midway for 6—8 weeks... 

Tau-fluvalinate Not applicable Bees No MRL required Not applicable No entry No entry... 

OJ column (250 x 2 mm ID) to separate the two isomers of tau-fluvalinate (A + B) with -hexane ethanol (90 10, vA ) as the mobile phase. The CHIRALCEL OJ column was purchased from GROM (Herrenberg-Kayh, Germany). 

Synthetic pyrethroids Acrinathrin, allethrin, biphenthrin, bioresmethrin, cyfluthrin, cypermethrin, deltamethrin, fenvalerate, etofenprox, fenpropathrin, flucythrinate, fluvalinate, lambda-cyhalothrin, permethrin, piperonylbutoxide, tau-fluvalinate... 

Cypermethrin I Cypermethrin II Cypermethrin III Cypermethrin IV Deltamethrin Fluvalinate tau-I Fluvalinate tau-II... 

Fluvalinate Table B17, Appendix B, gives the chiral configurations of the four individual isomers of fiuvalinate, their CAS no. for absolute stereochemistry, and enantiomer pairs. The strucmre of each stereoisomer is coded A-D making it easier to identify (label) each isomer. In Table B18, Appendix B, fluvalinate and tau-fiuvalinate are listed as the only technical products sold by registrants. Technical fiuvalinate contains all four isomers, while taM-fiuvalinate is limited to isomers A and B . 

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