Targeting to the Proximal Tubular Cell

5 Delivery of Drugs and Antisense Oligonunucleotides to the Proximal Tubular Cell 

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To date, only a limited number of studies have focused on drug delivery to the mesangium cell and only a modest degree of selectivity has been obtained in this respect [21,22]. More extensive studies have been performed on targeting drugs to the proximal tubular cell. Therefore, in this chapter, only targeting to the proximal tubular cell will be addressed. 

Figure 5.7. Schematic representation of the mechanism by which drug targeting to the proximal tubular cell of the kidney might be achieved using a low molecular weight protein (LMWP) as a carrier.

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