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Target flexibility

Beier C, Zacharias M (2010) Tackling the challenges posed by target flexibility in drug design. Expert Opin Drug Discov 5(4) 347-359... [Pg.11]

Emerson, A., Fanelli, F., Gohlke, H., Kuhn, LA., Morris, G.M., Orozco, M., Pertinhez, T.A., Rizzi, M., and Sotriffer, C.A. (2008) Target flexibility an emerging consideration in drug discovery and design. Journal of Medicinal Chemistry, 51 (20), 6237-6255. [Pg.240]

Table 9.1 Applications of docking-based methods incorporating target flexibility at different stages of the drug discovery/design process. [Pg.251]

Efficient cellular uptake Injectable into the circulation Capable of passive or active targeting Flexible chemistry... [Pg.97]

Potential for cell-specific targeting Flexible chemistry Potentially biocompatible... [Pg.3495]

See other pages where Target flexibility is mentioned: [Pg.25]    [Pg.268]    [Pg.91]    [Pg.28]    [Pg.187]    [Pg.237]    [Pg.246]    [Pg.249]    [Pg.250]    [Pg.250]    [Pg.250]    [Pg.252]    [Pg.252]    [Pg.253]    [Pg.256]    [Pg.257]    [Pg.260]    [Pg.1154]    [Pg.131]    [Pg.531]    [Pg.532]    [Pg.39]    [Pg.397]   
See also in sourсe #XX -- [ Pg.21 , Pg.28 ]



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