Tanacetum antiinflammatory activity

Antiinflammatory activity of Tanacetum species is caused by various kind of compoimds, such as sesquiterpenoids, flavonoids and essential oils. 

In a human polymorphonuclear leucocj e-based bioassay, it was determined that acetone extracts of the leaves of four Tanacetum species T. parthenium, T vulgare, T. ptarmiciflorum and T. niveum) inhibit phorbol myristate acetate-induced chemiluminescence of human polymorphonuclear leucocytes [186,187]. Brown et al. investigated the antiinflammatory activity of T. parthenium and a constituent of Ais plant, parthenolide. They suggested that parthenolide is not the only active constituent [187]. Hoult et al have announced that a flavonoid, tanetin is one of the active compounds presented in T. parthenium [156]. 

Antiinflammatory activity of the flavonoids [131,132,141,147,148,156,157] and essential oils [83,150,152,158] isolated from Tanacetum species were also reported. 

---