Tablet manufacture moisture effect

In an earlier section, the potential for a water-soluble substance to deliquesce was discussed. The emphasis here is on less obvious effects of moisture on solid dosage forms, and three associated areas that link to information presented earlier in this article are discussed 1) moisture-induced changes in the state of the solid 2) the effect of moisture on the performance of excipients in the manufacture of compressed tablets and 3) the chemical stability of bioactive agents alone and in combination with excipients. 

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