Systems biology, small molecule drug

Stemming from the use of pluronics as solubilizers for small molecule drugs, it became apparent that pluronics is more than just a simple dehv-ery system and provides beneficial biological effects both symbiotically with other treatments and alone. 

There are distinct differences in the manufacture of small and large molecule drugs the former is mainly based on organic chemical synthesis, while the latter relies on biological systems of recombinant DNA (rDNA) technology. In this chapter, we describe the manufacturing processes for these drugs under GMP environments. 

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