Systematic methodical platform

Method development to provide robust analyte-specific procedures from complex biomatrices has received significant attention. Modular on-line and off-line approaches have been reported that focus on a systematic and integrated approach to select optimal extraction and separation chemistries [27]. These approaches have automated data analysis, whereby the feedback loop from experimentation to decision can be significantly reduced [18]. Wells has comprehensively discussed the use of automated strategies for the rapid determination of optimal extraction chemistries to maximize analyte recovery and selectivity [28]. The book includes up-to-date information on available robotic platforms for automated sample preparation and comprehensive information on labware. 

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