Two-step synthesis

Gabriel synthesis Two-step preparation of primary amines from the corresponding alkyl halides using phthalimide as the nitrogen source. 182... 

Since the simplest F-l,3-dithietane (38) cannot be prepared by dimerization of thiocarbonyl fluoride, probably due to propensity of the latter to polymerize, a different synthetic approach is employed for its synthesis. Two-step process includes photocyclodimerization of Cl2C=S and Swarts-type fluorination of the dimer by antimony trifluoride to give 38 (Scheme 2.20). Compound 38 can be a source of very pure thiocarbonyl fluoride, when pyrolyzed at 500°C." ... 

The xerogels are materials that have precise microstructure and they are synthesized by sol-gel synthesis. Two steps are implied in the sol-gel process, hydrolysis and condensation, which are very sensitive to reaction conditions, being faster or slower and giving xerogels with different characteristics, in terms of structure, surface area, and porosity (Fidalgo and Ilharco, 2005). 

The addition of diester 178 to cyclic enone was apphed by Plaquevent et al. in the synthesis of methyl dihydrojasmonate, a natural ketone with olfactory properties isolated from Jasminum grandiforum L (Scheme 11.43). Despite the relatively moderate 80% ee and large excess of dimethyl malonate required (30 equiv), the rapidity of the synthesis (two steps to the natural product) and the simple reaction conditions remained attractive for scaleup. 

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See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

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