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Synthesis secu’amamine

In addition to these results, this methodology was successfully applied to the preparation of 3-deshydroxysecu amamine A (222), an unnatural analog of secu amamine (37). The synthesis started from protected piperidone 217 (Scheme 36). Two successive deprotonation/alkylation reactions produced the 2,6-trans product 218 in a good stereoselectivity (>8 1) and modest yield. Then, the ris-enyne side chain was installed in an efficient way by a... [Pg.90]


See other pages where Synthesis secu’amamine is mentioned: [Pg.3]    [Pg.3]    [Pg.61]    [Pg.88]    [Pg.88]    [Pg.88]    [Pg.89]    [Pg.89]    [Pg.90]   
See also in sourсe #XX -- [ Pg.88 , Pg.88 , Pg.89 ]




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Secu’amamine

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