Synthesis of Perfluoroalkyl Compounds

These compounds are generally prepared by the same methods used to synthesize trifluoromethylated compounds. A significant number of reactions described in the CF3 series are also applicable in higher series (C2F5, C3F7, C4F9). However, the synthesis of very highly fluorinated or perfluorinated compounds requires a more 

(a) RV. Ramachandran, Asymmetric Fluoroorganic Chemistry, ACS Symposium Series 746, ACS, Washington DC, 2000. (b) Fluorine-Containing Synthons, V.A. Soloshonok, Ed., ACS Symposium Series 911, ACS, Washington DC, 2005. 

Henry-dit-Quesnel, L. Toupet, J.C. Pommelet, and T. Lequeux, Org. Biomol. Chem. 2003, 1, 2486. 

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