Synthesis of High Molecular Weight Polypeptides

Synthesis of High Molecular Weight Polypeptides N-carboxy anhydrides of a-amino acids, viz. L-leucine, L-alanine, y-benzyl-L-glutamine and glycine undergo solid state polymerisation by using butylamine as an initiator in a hexane suspension at 20-50 C (Scheme 51). 

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