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Synthesis of heterocycles using amino-azirine building blocks

Synthesis of heterocycles using amino-azirine building blocks [Pg.218]

Reaction with 4-membered cyclic sulfonamides 8 afforded 7-membered heterocycles 9 in high yield (60-90%), and reaction with 6-membered sulfonamide 10 (n=l) proceeded in 85-99% yield incorporating all atoms of both building blocks into the products. No by-products were thus formed. [Pg.218]




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2/7-Azirine synthesis

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Amino heterocycles

Azirine

Block synthesis

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Synthesis of Building Blocks

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