Synthesis from Heterocycles

Ring Synthesis from Heterocycles 4.04.3.2.1 Ring opening... 

The most important oxirane syntheses are by addition of an oxygen atom to a carbon-carbon double bond, i.e. by the epoxidation of alkenes, and these are considered in Section 5.05.4.2.2. The closing, by nucleophilic attack of oxygen on carbon, of an OCCX moiety is dealt with in Section 5.05.4.2.1 (this approach often uses alkenes as starting materials). Finally, oxirane synthesis from heterocycles is considered in Section 5.05.4.3 one of these methods, thermal rearrangement of 1,4-peroxides (Section 5.05.4.3.2), has assumed some importance in recent years. The synthesis of oxiranes is reviewed in (B-73MI50500) and (64HC(19-1U). 

Synthesis from Heterocycles Containing Three Heteroatoms 336... 

Davis, A.C., and A.L. Levy Peptide Synthesis from Heterocyclic Inter-... 

Scheme 4.8 lH-1,2,3-Triazole synthesis from heterocyclic CH-active compounds. 

---