Syncope, pacemakers vasovagal

Sutton R, Brignole M, Menozzi C et al. for the Vasovagal Syncope International Study (VASIS) Investigators Dual-chamber pacing in the treatment of neuraUy mediated tilt-positive cardioinbibitory syncope pacemaker versus no therapy a multicenter randomized study. Circulation 102(3), 294—299 (2000). 

Connolly S, Sheldon R, Thorpe K, et al. Pacemaker therapy for prevention of syncope in patients with recurrent severe vasovagal syncope. Second vasovagal pacemaker study (VPSll) a randomized trial. JAMA 289, 2224—2229 (2003). 

The crucial issue is to identify individuals who could benefit from pacing. Pacemakers should be considered for patients with frequent and medically refractory vasovagal syncope in whom there is evidence for bradycardia. Patients with specific drug intolerances or contraindications may be considered earlier. The VASIS group proposed a classification of the hemodynamic collapse patterns seen on lilt testing for the purpose of identifying potential candidates for drug or pacemaker trials (35). 

Connolly SJ, Sbeldon R, Roberts RS, Gent M. Tbe North American vasovagal pacemaker study (VPS) a randomized trial of permanent cardiac pacing for the prevention of vasovagal syncope. J. Am. CoU. Cardiol. 33, 16—20 (1999). 

Raj SR, Koshman ML, Sheldon RS Five-year follow-up of patients with dual chamber pacemakers for vasovagal syncope [abstract]. Can J Cardiol 18, xxx (2002). 

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