Synclisia alkaloids

Symphytine lb 188 Symphytine N-oxide lb 243 Synclisia alkaloids la 314 Synephrine lb 229... 

The only naturally occurring alkaloid of this small group is (+)-norcycleanine (124)[which is really 7 -O-demethylcycleanine). This alkaloid is not as widely distributed as its R,K diastereoisomer (-)-norcycleanine (125). The (+)-isomer has only been isolated from two plants Isolona hexaloba (Annonaceae) and Stephania cepharantha (Menispermaceae), neither of which are a source of the (-)-isomer (which was found in four Menispermaceous genera Chondodendron, Cyclea, Epinelrum, and Synclisia. The base tetra-O-demethylcycleanine (128a) has been reported, but data was not available. 

Table IV. Number of BisBIQ alkaloids isolated from the gtmeaAlbertisia, Chondodendron, Curarea, Epinetrum and Synclisia.

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