Symptomatic treatment complaints

Failure to recognize that MDD underlies such complaints can lead to unnecessary and costly tests, as well as a delay in effective treatment. Complaints may also vary by age group. Common symptomatic issues are listed in Table 6-3. 

Increased fatigability, a sensation of weakness, loss of appetite, disturbance of the ability to concentrate, of memory and sleep, dizziness, and headache were characteristic changes in 66 men who had been exposed for four to eight yr to leaded gasoline. Their main complaint was reduced sexual potency and various disturbances of sexual function (Neshkov 1971). These complaints, for which no other cause than the Et4Pb exposure was known, subsided on four to eight weeks symptomatic treatment, after the exposure had ceased. 

Adverse effects The adverse events associated with (3 blockers may be avoided by starting treatment at very low doses. However, treatment can be associated with complaints of fatigue and weakness, which usually resolve in a few weeks, Sometimes it is necessary to decrease the dose of the (3 blocker or diuretic. Symptomatic bradycardia is another serious adverse effect of (3 blockers, and requires a decrease in the dose or sometimes cardiac pacing to allow the use of this vital medication, Hypotension is another potential side effect however, it is rarely seen as the therapy is started with a very low dose (3,25 mg twice a day for carvedilol, I mg for bisoprolol and 12,5 mg for extended release metoprolol). The administration of ACE inhibitor and diuretic at a different time of day than the (3 blocker can... 

The indication for antiviral treatment of chronic hepatitis C is principally based on the following criteria (1.) a symptomatic course (subjective complaints, elevated transaminases, extrahepatic manifestations), (2.) inflammatory activity and progressive fibrosis or cirrhosis, and (i.) an infection risk regarding contact persons. 

For perimenopausal depression, antidepressants usually are dosed daily at standard dosages for major depression, although some women may respond to lower doses. Estradiol deficiency may decrease the activity of 5-HT and decrease the efficacy of antidepressants. Two open-label studies have reported that citalopram in doses of 20-60 mg/day was effective in treating depression in peri- and postmenopausal women and had augmenting effects in depressed subjects who were still symptomatic after treatment with transdermal estradiol (i.e., improved symptoms of anxiety and somatic complaints). " ... 

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