Sympathomimetics rhinitis

Ephedrine (25 to 50 mg p.o. t.i.d.) is indicated in the treatment of allergic disorders such as bronchial asthma nasal congestion in acute coryza vasomotor rhinitis, acute sinusitis, and hay fever. Ephedrine (25 to 30 mg slowly SC, IM, or IV) has been used to relieve acute bronchospasm, but epinephrine is more effective. Ephedrine is also used in shock. It is a naturally occurring sympathomimetic agent that stimulates alpha and beta receptors and CNS. It is less potent than epinephrine but has a longer duration of action (see also Figure 37). 

Topical decongestants do not commonly cause systemic sympathomimetic effects but may lead to rebound congestion (rhinitis medicamentosa) after 5-7 days of therapy. 

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