Sweat, thiamin

Sweat may contain up to 30 to 60 nmol of thiamin per L. In very hot conditions, this may represent a significant loss of the vitamin. 

SCHIFF (1941) refers to a similar case in which a patient received a series of intramuscular injections of 25 mg dosages within a period of 7 months using three different commercial preparations. After the last injection, nausea, vomiting, profuse sweating, and collapse occurred showing the signs of severe shock. On closer interrogation, it was found that the patient had had several brief episodes of nasal symptoms and nausea after the previous injections. An intradermal test with an aqueous solution of thiamine hydrochloride was also positive in this case. In view of the rapidity with which the reaction occurred, the author assumed that some of the thiamine hydrochloride solution must have been administered intravenously at the last injection. 

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