Survival and ventricular enlargement

Vantrimpont P, Rouleau JL, Wun CC, for the SAVE Investigators. Additive beneficial effects of beta-blocker to angiotensin-converting enzyme inhibitor in the Survival and Ventricular Enlargement (SAVE) Smdy. J Am Coll Cardil 1997 29 229-36. 

Abbreviations. AIRE, acute Infarction ramipril efficacy CONSENSUS, cooperative north Scandinavian enalapril sur/f/a study HF, heart failure LVEF, left ventricular ejection fraction NYHA. New York Heart Association SAVE, survival and ventricular enlargement SMILE, survival of myocardial infarction long-term evaluation SOLVD. studies of left ventricular dysfunction TRACE, trandolapril cardiac evaluation study group. 

Pfeffer MA, Braunwald E, Moye LA, et al. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators, N EnglJ Med 1992 327 669-677. 

SAVE = Survival and Ventricular Enlargement Trial AIRE = Acute Infarction Ramipril Efficacy study CONSENSUS = Cooperative New Scandinavian Enalapril Survival Study. References Rutherford J D et al 1994 Effects of captopril on ischemic events after myocardial infarction. Results of the Survival and Ventricular Enlargement trial. SAVE Investigators. Circulation 90 1731-1738. AIRE Study Investigators 1993 Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure. Lancet 342 821-828. Swedberg K P et al 1992 Effects of the early administration of enalapril on mortality in patients with acute myocardial infarction. New England Journal of Medicine 327 678-684. 

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