Suppressor solid-phase reagents

Another technique of improving the S/N ratio is the one that uses postcolumn addition of a solid-phase reagent (SPR), which is a colloidal suspension of ul-trafine ion-exchange particles. The SPR reacts with the analyte to increase its conductivity. Additionally, the SPR has a low electrophoretic mobility and, hence, conductance. This technique avoids the dead time due to suppressor column and also eliminates the regeneration cycle. 

Later, electrochemically regenerated suppression modules were introduced, where an electrochemical process is used to regenerate a solid-phase chemical suppressor for continuous reagent-free operation. Selfregenerating suppressors are similar to micromembrane suppressors, except that regenerant hydronium and hydroxide ions are produced, in situ, by electrolysis of water supplied by recycle or an external source. 

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