Supported ionic liquid phase catalysis

Highly polar organocatalysts such as amino acids and peptides are almost insoluble in conventional organic solvents, but they are soluble in ionic liquids. Because of these physical properties, asymmetric syntheses in ionic liquids under biphasic condition have been reported [124]. Recently, combinations of solid catalysts and ionic hquids have been studied intensively. The supported ionic liquid phase catalyst is a new generation of the supported liquid-phase catalyst [125]. The supported ionic Hquid phase catalyst 232 is readily prepared by adsorption of (S)-proline 13 

7 Review of the mechanism of organocatalytic reactions Cheong, P.H.-Y., Legault, C.Y., Urn, J.M., Celebi-Olcum, N., and Honk, K.N. 

23 Review of organocatalytic cyclizations Moyano, A. and Rios, R. (2011) Chem. Rev., Ill, 4703-4832. 

25 Reviews of primary amine-based organocatalyst (a) Xu, L-W., Luo,., and Lu, Y. (2009) Chem. Commun., 

30 Review of aldol reaction in water Mlynarski, J. and Paradowska,). (2008) Chem. Soc. Rev., 37,1502-1511. 

31 Reviews of organocatalytic reactions in water (a) Mase, N. and Barbas, C.F, 

63 Review of organocatalytic vinylogous aldol reactions Pansare, S.V. and Paul, E.K. (2011) Chem. Eur. J., 17, 8770-8779. 

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Hintermair, U. and Zhao, G. and Santini, C.C. and Muldoon, M.J. and Cole-Hamilton, D.J. (2007). Supported ionic liquid phase catalysis with supercritical flow. Chem. Commun., 14, 1462-1464. 

C jimlfPFe] Pd(OAc)2 Pd(PPh3)4 Et3N k2co3 100-150 °C. Supported ionic liquid phase catalysis (SILP) with silica as solid phase catalyst relatively stable for at least 5 runs product decanted and solid phase washed with hexane less than 0.24% catalyst loss. [87]... 

Figure 2.13 Examples of three concepts of catalysis in supported ionic liquids (a) hydroformylation catalysis [121] (b) methanol carbonylation [122] (c) supported ionic liquid phase catalysis combined with SCCO2 [127].

Rodrfguez-Perez L, Teuma E, Falqui A et al (2008) Supported ionic liquid phase catalysis on functionalized carbon nanotubes. Chem Commun 35 4201 203... 

Hydroformylation of olefins in supported ionic liquid-phase catalysis... 

Table 5.6-3 Evaluation of the hydroformylation reaction ofi-hexene to form n,iso-heptanal using supported ionic liquid phase catalysis (SILP), biphasic catalysis and homogeneous catalysis [88]...

Wasserscheid, R. van Hal, Supported Ionic Liquid Phase Catalysis-Heterogenization of Homogeneous Rhodium Phosphite Catalysts in Ionic... 

This modern method, commonly known supported ionic liquid phase catalysis, is based on the simple chemical attachment of ILs to the support surface or the simple deposition of the catalytically active speciesmain idea for the preparation of these alternative materials is to avoid or at least decrease the deactivation of the catalyst after reactions as well as to minimize the amount of IL used in each process. In addition, the SILP method provides some advantages compared to other catalytic systems. For example, SILP catalytic systems offer the elimination/reduction of mass transfer limitations and give access to more robust/recyclable catalysts with an easy separation after reactions. In other words,... 

Riisager, A. and Fehrmann, R. (2006) A process for continuous carbonylation by supported ionic liquid-phase catalysis. WO 2006/122563, Danmarks Tekniske Universitet. 

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