Superstable hairpin structures in large RNAs

Superstable hairpin structures in large RNAs Any secondary structure which originates from folding of a single-stranded RNA is by definition dominated by hairpins [155]. The folding into hairpins 

The preference has both thermodynamic and structural reasons. Initially the sequence dependence of the hairpin-loop thermodynamic stability was attributed 

Melting temperatures and free energies of hairpin formation for members of the UUCG family of stable RNA hairpins 

The structural features of the GAAA DNA loop are qualitatively consistent with the structure determined for its RNA analogue. This loop is found in phage 0X174 at the origin of replication and herpes simplex virus, in the promoter region of an E.coli heat shock gene, and at virion RNA polymersase promoters. 

Melting temperatures for members of the GNRA family of stable DNA hairpins  

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