Sulphonamides for urinary infections

A number of sulphonamides have been used extensively for the prevention and cure of urinary-tract infections over the past few decades. They are used sometiems as a prophylactic before and after manipulations on the urinary tract. A few such sulphanilamide analogues belonging to this category shall be dealt with here. 

Examples sulfacetamide, sulfafurazole, sulfisoxazole acetyl, sulfacitine, etc. 

It is prepared by the selective and partial hydrolysis of the N, N -diacetyl derivative of sulphanilamide which is obtained by the aeetylation of sulfanilamide. 

It possesses general characteristics of a sulphonamide and was formerly used in the treatment of bacterial infeetions of the urinary tract. 

4-Dimethyl-5-isoxazolyl) sulfanilamide Benzenesulfonamide, 4-amino-N-(3,4-dimethyl-5-isoxazolyl)- BP USP Ind. P Int. P  

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See also in sourсe #XX -- [ ]

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