Sulforaphane, structure

Scheme 9 Formation of (S)-(-)-goitrin 24 and structure of sulforaphane. In 25, e represents a lone pair of electrons...

Fig. 6. Biotransformation of sulforaphane through mercapturic acid metabolic pathway. It is hypothesized that SFN-NAC or SFN-Cys are active FIDAC inhibitors. The structures of SFN-Cys and SFN-NAC are also shown.

Zhang Y, Kensler TW, Cho CQ Posner GH, Tallalay P. (1994) Anticarcinogenic activities of sulforaphane and structurally related synthetic norbomyl isothiocyanates. Proc Natl Acad Sci USA 91 3147-3150. 

Zhang, Y., Kensler, T.W., Cho, C.G., Posner, G.H. and Talalay, P. (1994) Anticarcino-genic activities of sulforaphane and structurally-related synthetic norbomylisoth-iocyanates. Proc. Natl. Acad. Sci. USA, 91, 3147-50. 

Figure 1 Chemical structures of glucoraphanin and sulforaphane and the myrosinasecatalyzed conversion...

Figure 4 The chemical structure of sulforaphane conjugated with glutathione...

Posner GH, Cho C-G, Green JV, Zhang Y, Talalay P. Design and synthesis of bifunctional isothiocyanate analogs of sulforaphane correlation between structure and potency as inducers of anticarcinogenic detoxification enzymes. J Med Chem i994 37 i70-i76. 

O 63. The "Chemistry in Focus" segment Broccoli-MiTocle Food discusses the health benefits of eating broccoli and gives a Lewis structure for sulforaphane, a chemical in broccoli. Draw possible resonance structures for sulforaphane. 

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