Sulfonylamino-oxazoline

A benzene solution of cyclohexenecarbonitrile (45) and 10 mol% of Pd(OAc)2 with chiral sulfonylamino-oxazoline ligand 47 in the presence of one equiva-... 

In 1999, Mikami and co-workers reported the first example of asymmetric Fujiwara-Moritani reaction catalyzed by Pd" and sulfonylamino-oxazoline ligand (Scheme 5.12a). A 1 1 complex between the chiral ligand and Pd(OAc)2 could be the active catalyst in this asymmetric Fujiwara-Moritani reaction. This method provides a convenient process to synthesize aromatic C—H bond activation/olefin coupling products but with moderate enantioselectivity. 

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