Sulfonyl Azides in Huisgen Cycloaddition

CuAAC could well be the most direct and practical route to 1-sulfonyl-1,2,3-triazoles. The cycloaddition between copper(l) acetyUdes and sulfonyl azides gives AT-acylsulfonamides in aqueous medium [85] and amidines in the presence 

1-Vinyl-l,2,3-triazoles have been synthesized in moderate yields by the cycloaddition of vinyl azides and phenyl acetylene, using acetone or dioxane as solvent, in a flow microreactor where copper wire was inductively heated. The copper metal was directly and instantaneously heated inside the reactor, which results in a higher reactivity than with conventionally heated elemental copper [88]. 

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