Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Sugar protecting group

OPArs, N(R)PAr2, OP(OAr)2, OAsArj, Prj variable configuring the sugar protecting group... [Pg.478]

In conclusion, a facile, new method for the synthesis of 2-deoxy-N-glycosylamides has been developed. This method utilizes simple starting materials in a one pot protocol. The addition reaction is sensitive to electronic effects of both the sugar protecting groups and the substituents on the amide. The sterochemical outcomes and yields of the addition reaction are also dependent on the choice of solvent employed. High selectivity is achieved in the... [Pg.57]

By studying the effects of substitution at the 6-position of purine deoxynucleosides, further evidence has been obtained that the rate-limiting step in acid-catalysed hydrolysis is the departure of the protonated base moiety with concomitant formation of an oxocarbonium ion. The rate constants for acid hydrolysis of several N -substituted 2 -deoxyadenosines were measured in order to assess the role of various N - and sugar-protecting groups in depurination reactions observed in oligonucleotide synthesis the exceptional lability of N -acyl derivatives can be accounted for by N protonation, as determined by n.m.r. Kinetic parameters have also been determined for the multistage reactions of 6-substituted purine... [Pg.218]

Effect of the sugar protecting groups, Chem. Lett. 1401 (1985). [Pg.51]

See other pages where Sugar protecting group is mentioned: [Pg.315]    [Pg.68]    [Pg.105]    [Pg.201]    [Pg.53]    [Pg.91]    [Pg.181]    [Pg.209]    [Pg.656]    [Pg.342]    [Pg.197]    [Pg.227]    [Pg.273]    [Pg.340]    [Pg.192]    [Pg.135]    [Pg.340]    [Pg.145]    [Pg.42]    [Pg.263]    [Pg.265]    [Pg.267]    [Pg.280]   
See also in sourсe #XX -- [ Pg.53 ]

See also in sourсe #XX -- [ Pg.145 ]



SEARCH



Protecting group for sugars

Sugar groups

Sugars protection

© 2024 chempedia.info