Sugar Containing Polyester

Two-step synthesis of sugar-containing polyesters by lipase CA catalyst was reported (Scheme 13)." Lipase CA catalyzed the condensation of sucrose with an excess of divinyl adipate to produce sucrose 6,6 -O-divinyl adipate, which was reacted with a,oo-alkylene diols by the same catalyst, yielding polyesters containing a sucrose unit in the main chain. This method conveniently affords... 

Figure 8. Enzymatic synthesis of sugar containing polyesters using adipic acid esters...

It has also been shown that lipase CA can produce reduced sugar-containing polyesters regioselectively from divinyl sebacate and sorbitol, in which sorbitol was exclusively acylated at the 1 and 6-positions (Scheme 23.11) [115]. Mannitol and meso-erythritol were also regioselectively polymerized with divinyl sebacate. The lipase CA-catalyzed polycondensation of adipic acid and sorbitol also took place in... 

Another approach of enzymatic synthesis of sugar-containing polyesters was demonstrated (123). Lipase CA-catalyzed reaction of sucrose or trehalose with an excess of divinyl adipate produced 6,6 -diacylated product having vinyl esters at both ends, which was employed as monomer in the enzymatic polycondensation with various glycols, jdelding linear polyesters with Mw up to 2.2x 10. ... 

Unsaturation within the fatty acid chain did not disturb the process. In the polymerisation of divinyl sebacate and polyol (sorbitol), the regioselectivity was controlled to yield sugar-containing polyesters in which the 1- and 6-positions of sorbitol were regioselectively acylated. 

Functional polyesters were synthesized through the specific catalysis of lipase, and their properties and functions were evaluated. Enantio- and regioselec-tive polycondensations produced chiral and sugar-containing polyesters, respectively [20,23]. Using lipase catalyst reactive polyesters were conveniently obtained, some of which were crosslinked to biodegradable coatings. Recently, polyester-based biomaterials have been developed by lipase-catalyzed polymerizations. 

Two-step synthesis of sugar-containing polyesters by lipase CA catalyst was reported (Scheme 11) [101]. Lipase CA catalyzed the condensation of sucrose... 

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