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Substrate specificity of serine proteases

Eiectrostatics piays an important role also in substrate specificity of serine proteases. We formulated the similis simili gaudet principle stating that electrostatically similar regions of interacting partners, characterized by MEF values of the same order of magnitude, tend to associate more readily than dissimilar ones. Point mutation experiments on subtilisin support this hypothesis. ... [Pg.910]


See other pages where Substrate specificity of serine proteases is mentioned: [Pg.250]    [Pg.427]   
See also in sourсe #XX -- [ Pg.616 ]

See also in sourсe #XX -- [ Pg.616 ]

See also in sourсe #XX -- [ Pg.616 ]

See also in sourсe #XX -- [ Pg.616 ]




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