Substrate in biochemical reactions

Lethal Synthesis. This is a process in which the toxic substance has a close stmctural similarity to normal substrates in biochemical reactions. As a result, the material may be incorporated into the biochemical pathway and metabolized to an abnormal and toxic product. A classic example is... 

S-Adenosyl-L-methionine as sulfonium compound could transfer its methyl group as CH3 to nucleophile centers of substrates in biochemical reactions. 

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