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Substitution of a-Amino Acid Derivatives via PTC

Recently, asymmetric PTC using chiral quaternary ammonium salt 110 has proven to be an effective method for the enantioselective a-arylation of a-imino acid derivatives 108 via asymmetric nucleophilic aromatic substitution, to give a,a-disubstituted a-amino acids 111 in good to high enantiomeric purity (Scheme 8.22) [86]. [Pg.212]


See other pages where Substitution of a-Amino Acid Derivatives via PTC is mentioned: [Pg.135]    [Pg.135]    [Pg.139]    [Pg.143]    [Pg.145]    [Pg.149]    [Pg.135]    [Pg.135]    [Pg.139]    [Pg.143]    [Pg.145]    [Pg.149]    [Pg.147]    [Pg.102]    [Pg.236]   


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A-Substituted amino acid derivatives

A-Substituted derivatives

A-amino acid derivatives

Amino acid derivatives

Amino acids deriv

Amino substitution

Amino-substituted derivatives

PTC amino acid

PTC derivatives

PTC-124

Substituted derivatives

Substituted derivatives of

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