6-Substituted benzimidazo quinazolines

Devi, R.R. and Reddy M.S., Synthesis of 6,7-dihydro-6-substituted benzimidazo [ 1,2-c Jbenzo [y ] quinazolines and their heteroaromatic analogues, Indian J. Chem. 1994, 33B, 1013-1016. 

MWI promoted the synthesis of fused quinazolines with bridge-head nitrogen by cyclocondensation of 2-(2-aminophenyl)benzimidazole (586) with orthoesters to give 6-substituted benzimidazo[l,2-c]quinazolines 588 in 85-94% yields after irradiation... 

The isomeric imidazo[l,5-a]pyrimidine (161) gave the 1,3-dibromo derivative when exposed to bromine or NBS (72BSF2481). Iodination of benzimidazo[2,l- >]quinazolin-12(5 or 6//)-ones was accomplished by boiling them with bromine in the presence of sodium or potassium iodide. Substitution took place at the 9-position in the benzimidazo moiety (91MI3). 

Frere, S., Thiery, V., Bailly, C. and Besson T., Novel 6-substituted benzothiazol-2-yl indolo[l,2 c jquinazo lines and benzimidazo[l,2-c]quinazolines, Tetrahedron, 2003,59, 773-779. 

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