Subcutaneous plexus

Arteries entering the skin arise from more substantial vessels located in the subcutaneous connective tissue. These offshoots form a plexus just beneath the dermis [11]. Branches from this subcutaneous network directly supply blood to the hair follicles, the glandular appendages, and the subcutaneous fat. Branches to the upper skin from this deep plexus divide again within... 

A 36-year-old woman developed supraclavicular skin necrosis, followed by sloughing of subcutaneous tissue down to the first rib, including the dorsal roots of the brachial plexus, after receiving an interscalene block followed by an infusion 5 months later she still had complete sensory and motor paralysis of the C5 nerve root requiring nerve grafting. 

Endorphin Analogs - D-Ala, N-MeMet -enkephallnamide ( ) has been found to be a potent parenteral analgesic.59 it was 238 times as potent as normor-phlne in the mouse vas deferens assay, and four times as potent as morphine in the mouse hot plate assay (jump response) after subcutaneous administration. It is claimed that has relatively little respiratory depressant properties or tendency to cause tolerance or physical dependence. A series of Met -enkephalin analogs extended at the amino terminus with amino acid residues corresponding to 6-LPH have been described. Using the guinea-pig ileum-myenteric plexus assay, potency was found to decrease dramatically on further extension of the g-LPH 60-65 sequence... 

Figure 13.18 Diagrammatic representation of the positioning of the lymphatic plexus in relation to dermal papillary blood vessels and subcutaneous tissue sites.

Hypodermis and the subcutaneous tissue are made up of lobules of adipose tissue surrounded by partitions of thin connective tissue which form septae, through which pass the large arterial and venous blood vessels destined for the skin, and which supply two parallel vascular plexuses, located partly below the reticular dermis and also immediately under the epidermis. 

Once in the blood, ample evidence now suggests that aluminum Ccm cross the blood-brain barrier to enter the brain. Liss, using newborn rabbits, found that aluminum chloride ingestion by the mother rabbit resulted in increased aluminum content in the mother s milk and in the brains of the suckling rabbits. It is impor-temt to remember, however, that the blood-brain barrier may not have been fully formed in the infant rabbits. DeBoni et al. subjected adult rabbits to repeated subcutaneous injections of aluminum. Atomic absorption spectroscopy showed that brain aluminum levels increased from 1.1 xg/g diy weight (controls) to 2.5-47.9 Xg/g in injected animals. Using the aluminum-sensitive Morin stain, th found that neutrophils and monocytes within vessels and capillary endothelial cells exhibited intensely fiuores-cent nuclei, whereas the nuclei of cells of the choroid plexus were... 

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