Structural Genomics Centers

This last case was indeed very rare until recently. The advent of structural genomics projects has resulted in an unprecedented number of protein structures deposited in the PDB identified as hypothetical proteins. The number of structures labeled as hypothetical protein or unknown function ranges from 30 to 60% of the total number of depositions depending on the structural genomics center, and this number is increasing exponentially. Currently, the number of structures of hypothetical proteins deposited in the PDB doubles every six months. 

Joint Center for Structural Genomics Berkeley Structural Genomics Center TB Structural Genomics Consortium Ontario Cancer Institute/University of Toronto/Pacific Northwest National Laboratory/University of British Columbia/McGill University Center for Advanced Research in... 

Doyle, D. A., Oppermann, U. C., Sund-strom, M. (2007) The scientific impact of the Structural Genomics Consortium a protein family and ligand-centered approach to medically-relevant human proteins. J Struct Funct Genomics 8, 107-119. 

Joint Center for Structural Genomics, (Jcsg), To be Published Crystal Structure Of Myo-Inositol-1-Phosphate Synthase- Related Protein (Tml419) From Thermotoga Maritima At 1.70 A Resolution, (Release date Mar 23, 2004)... 

I thank the members of the Bioinformatics Core of the Joint Center for Structural Genomics for their intellectual and material support and helpful discussions. I also thank to Anna Canaves for her assistance in manuscript preparation, critical reading, and contributions to graphics design. 

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