Structural Classification of Proteins database

Murzin A G, S E Brenner, T Hubbard and C Chothia 1995. SCOP A Structural Classification of Proteins Database for the Investigation of Sequences and Structures. Journal of Molecular Biology 247 536-540. 

TJ Hubbard, B Alley, SE Brenner, AG Murzm, C Chothia. SCOP A structural classification of proteins database. Nucleic Acids Res 27 254-256, 1999. 

FIGURE 4-22 Organization of proteins based on motifs. Shown here are just a small number of the hundreds of known stable motifs. They are divided into four classes all a, all /3, all3, and a + /3. Structural classification data from the SCOP (Structural Classification of Proteins) database (http //scop.mrc-lmb.cam.ac.uk/scop) are also provided. The PDB identifier is the unique number given to each structure archived in the Protein Data Bank (www.rcsb.org/pdb). The a//3 barrel, shown in Figure 4-21, is another particularly common a/fS motif. 

PALI (Phylogeny and Alignment of Homologous Protein Domains) Database. The PALI (v 2.6) database provides three-dimensional structure-based sequence alignments for homologous proteins of known three-dimensional structure (24-26). The protein families have been derived from the SCOP (Structural Classification of Proteins) database (27). There are 2,518 protein families, and using more than one sequence as reference, 37,986 profiles have been generated. 

Murzin AG, Brennerm SE, Hubbard T et al (1995) SCOP a structural classification of proteins database for the investigation of sequences and structures. J Mol Biol 247 536-540... 

Hubbard, T. J., et al., SCOP, Structural Classification of Proteins database applications to evaluation of the effectiveness of sequence alignment methods and statistics of protein structural data. Acta Crystallogr D Biol Crystallogr, 1998. 54(1 (Pt 6)) p. 1147-54. 

Murzin, A. G., Brenner, S. E., Hubbard, T., and Chothia, C., 1995. SCOP A structural classification of proteins database for the investigation of sequences and structures./. Mol. Biol 247 536-540. Hadley, C., and Jones, D. T., 1999. A systematic comparison of protein structure classification SCOP, CATH and FSSP. Structure Fold. Des. 7 1099-1112. 

SCOP A Structural Classification of Proteins Database for the Investigation of Sequences and Structures. 

Structural Classification of Proteins database widt information on folds and families. URL of World Wide Web server at http //scop.mrc-lmb.cam.acuk/scop/. UNIX workstations and Macintosh. 

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